Who do I contact?Ī- Great! send it to sarver at umn dot edu Q- I have an awesome suggestion for your database. Q- I don't see the differential expression of my favorite miRNA eg. Q- Is their a potential for batch affects to be interpreted as differential expression in the advanced search results? University of Minnesota Medical School researchers say tumor-secreted exosomes help some cancer cells to evade immune response of current FDA-approved treatment options MINNEAPOLIS/ST.PAUL () In a recent discovery by University of Minnesota Medical School, researchers uncovered a new way to potentially target and treat late-stage colorectal cancer a disease that kills. For example the Osteosarcoma tissue results show the results of comparing Osteosarcoma verses the combination of GIST, MFH, FIbromatosis, and Synovial Sarcoma. immunotherapies,' said Subree Subramanian, Ph.D., an associate professor in the U of M.

Write a command which lists all files and directories in the subtree of current. Q- What statistics are used to generate the the statistics view?Ī- The results shown in the statistics view are the results provided for a two group T-test comparing the stated tissue with the remaining tissues found in each phase. To Czech students I recommend to check the web pages of the UNIX lab. For advanced search, all data is quantile normalized together. Q-Some of the miRNA sequences can be found at multiple locations with different names why can I find only only one used here?Ī-We needed a unique name for each probe so for the 7 probes that had multilpe names in phase 2,3,4 the first miRNA name was used.Ī- Each phase was seperatey quantile normalized for basic search. There are over 338000 data-points currently in the dataset.Ī- Some miRNA names end in 9.1 becasue they are based off build 9.1 of the miRNA database and this changed in 9.1 relative to previous values. Thus on the whole, the repository consists of 25 tissue types representing 330 samples. Phase 4 consists of 1134 miRNAs and 54 tissues.

Phase 3 consists of 1134 miRNAs and 95 tissue. Phase 2 consists of 1134 miRNAs and 92 tissues. Mike Silverman, Das lab, Massachusetts General Hospital: Consortium member. Phase 1 consists of 739 miRNAs and 89 tissues. Subbaya (Subree) Subramanian, University of Minnesota: Guest speaker: 12 July 2018: Video not available. Q- What is included in the S-MED Database?Ī- Currently the database hosts data from four different experimental phases. hsa-miR-335 would appear missing in experimental phase 2,3,4and hsa-miR-335-3p and -5p would appear missing in experimental phase 1. Additionally, a single miRNA probe may in later versions have been split into two different probes for example inphase 1 hsa-miR-335 is present in phase 2 this is now called hsa-miR-335-3p and hsa-miR-335-5p. One explanation is that many additional probes were included in phase 2,3,4 that were not present in phase 1. This can occur for a few different reasons. S-MED Frequently Asked QuestionsĪ- If a blank space is shown in a heatmap or in a data table, a value is not present in the database for the miRNA. Colon Cancer - microRNA Expression Database CC-MED S-MED (Sarcoma Expression Database) F.

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